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. 2014 Feb 21;9(2):e88894. doi: 10.1371/journal.pone.0088894

Figure 4. Representative immunohistochemical staining of PAR-1, PAR-2, PAR-3 and PAR-4 in human renal biopsies.

Figure 4

Expression of PARs was demonstrated in renal tissue from patients with biopsy proven diabetic nephropathy (F–I) and non-diabetic control subjects (A–D). Isotype-matched negative control was shown in diabetic nephropathy section (J) and non-diabetic control (E). Magnification: 400X. Quantitative analysis of PAR staining by Image Pro Plus 6.0 software (K); IOD, Integrated Optical Density. **p<0.01; ***p<0.001 compared with control.