Figure 6.

Dose-dependent induction of DNA damage (comet assay) in MCF-7 cells after nickel nanoparticle (Ni NP) exposure. (A) Percent tail DNA and (B) Olive tail moment (arbitrary unit).^a (C) Significant positive correlations between reactive oxygen species (ROS) and DNA damage (% tail DNA) in MCF-7 cells after 24 hours’ exposure to 10, 25, and 50 μg/mL of Ni NPs.

Notes: ^aData represented are mean ± standard deviation of three identical experiments made in triplicate. *Significant difference compared with the control (P<0.05).

Abbreviation: au, arbitrary unit.