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. 2013 Dec 21;12:170. doi: 10.1186/1476-4598-12-170

Table 2.

List of the studies of Chr1q and/or CHD1L amplification in cancer

Tumor origin Chr1q/CHD1L Technique used Biological/clinical impact References
Breast
Chr1q (Inline graphic 67%)
CGH
genetic aberration
[6]
Bladder
Chr1q (Inline graphic 54%)
CGH
Invasive cancer
[5]
CHD1L Inline graphicInline graphic
PCR
Poor prognosis
[31]
Chr1q21-24 Inline graphic
CGH + expression
Survival genes
[26]
Colorectal
CHD1L Inline graphicInline graphic
FISH, PCR
Oncogene, Poor survival
[11]
Esophageal
Chr1q Inline graphic
CGH
Genetic aberration
[9]
Fibrosarcoma
CHD1L Inline graphic
CGH
Genetic defect
[10]
Liver
Chr1q21
CGH
Poor prognosis
[8]
(Inline graphic 56 ~78%)
FISH
CHD1L was
[12]
Chr1q21 Inline graphic
TMA + IHC
Sequenced
[29]
CHD1L Inline graphic
 
Poor prognosis
 
CHD1L Inline graphic
 
 
 
Ovarian CHD1L Inline graphic TMA + IHC Metastatic cancer with poor prognosis [30]