Table 2.
List of the studies of Chr1q and/or CHD1L amplification in cancer
Tumor origin | Chr1q/CHD1L | Technique used | Biological/clinical impact | References |
---|---|---|---|---|
Breast |
Chr1q (![]() |
CGH |
genetic aberration |
[6] |
Bladder |
Chr1q (![]() |
CGH |
Invasive cancer |
[5] |
CHD1L ![]() ![]() |
PCR |
Poor prognosis |
[31] |
|
Chr1q21-24 ![]() |
CGH + expression |
Survival genes |
[26] |
|
Colorectal |
CHD1L ![]() ![]() |
FISH, PCR |
Oncogene, Poor survival |
[11] |
Esophageal |
Chr1q ![]() |
CGH |
Genetic aberration |
[9] |
Fibrosarcoma |
CHD1L ![]() |
CGH |
Genetic defect |
[10] |
Liver |
Chr1q21 |
CGH |
Poor prognosis |
[8] |
(![]() |
FISH |
CHD1L was |
[12] |
|
Chr1q21 ![]() |
TMA + IHC |
Sequenced |
[29] |
|
CHD1L ![]() |
|
Poor prognosis |
|
|
CHD1L ![]() |
|
|
|
|
Ovarian | CHD1L ![]() |
TMA + IHC | Metastatic cancer with poor prognosis | [30] |