Table 5. In-silico functional prediction of critical variants of ABCB1 SNPs.
| SNP | FunctionalCategory | Prediction tool | Prediction effect | FS score |
| rs1128503 | Splicingregulation | ESEfinder | Not changed | 0.407 |
| ESRSearch | Changed | |||
| PESX | Changed | |||
| RESCUE ESE | Changed | |||
| rs2032582 | Proteincoding | PolyPhen | Benign | 0.418 |
| SIFT | No prediction | |||
| SNPeffect | Deleterious | |||
| LS-SNP | Deleterious | |||
| SNPs3D | Deleterious | |||
| Ensembl-NS | Nonsynonymous | |||
| Splicingregulation | ESEfinder | Changed | ||
| ESRSearch | Changed | |||
| PESX | Not changed | |||
| RESCUE ESE | Not changed | |||
| Posttranslation | KinasePhos | Not exist | ||
| OGPET | Exist | |||
| Sulfinator | Not exist | |||
| rs1045642 | Proteincoding | PolyPhen | Benign | 0.528 |
| SIFT | Tolerated | |||
| SNPeffect | Benign | |||
| LS-SNP | Benign | |||
| SNPs3D | Deleterious | |||
| Ensembl-NS | Nonsynonymous | |||
| Splicingregulation | ESEfinder | Changed | ||
| ESRSearch | Changed | |||
| PESX | Changed | |||
| RESCUE ESE | Not changed | |||
| Posttranslation | KinasePhos | Not exist | ||
| OGPET | Not exist |
FS Score; Functional significance score.