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Histopathology of mice with AdCre bladder injection.
| AdCre Bladder | p53ww/TSC1ww | p53cc/TSC1cc | p53ww/TSC1cc | p53cc/TSC1ww |
|---|---|---|---|---|
| Total | 13 | 26 | 23 | 22 |
| Death | 1 (8%) | 15 (58%) | 4 (17%) | 4 (18%) |
| Mesothelioma | 0 | 16 (73%)** | 0 | 0 |
| Unknown cause of death* | 1 | 4 | 4 | 4 |
Note that many mice that died were not found soon after death, so that necropsy could not be performed to determine a cause of death.
16 (73%) reflects the fraction of mice in which the presence of mesothelioma could be assessed (22).
