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. 2014 Feb 21;9(2):e89462. doi: 10.1371/journal.pone.0089462

Figure 4. Association between HIV-1 tropisms and CD4+T cell count using two genotypic algorithms.

Figure 4

The statistical significance of association between CXCR4- and CCR5-tropic strain infections and CD4+T cell count (Median and Interquartile Range [IQR]) was evaluated using the Two Independent Samples Nonparametric Tests (Man-Whitney U). Algorithm I: Geno2pheno (FPR = 10%) and webPSSM in combination, Algorithm II: Geno2pheno (FPR = 5%) and webPSSM in combination. X4 in light-grey square and R5 in dark-grey square were indicated as CXCR4- and CCR5-tropic strains, respectively.