Table 1. Protective effect of quercetin on the development of preimplantation mouse embryos against H2O2-induced oxidative injury.
| Zygotes developing to: n (% of A) | |||||||
| Groups | Conc. of H2O2 (μM) | Conc. of Que (μM) | No. of zygotes (A) | Two–cell stage | Morula stage | Blastocyst stage | Hatched stage |
| Control | 0 | 0 | 274 | 272 (99.270) | 241 (87.956) | 218 (79.562) | 126 (45.985) |
| H2O2 | 35 | 0 | 182 | 164 (90.110) *** | 117 (64.286)*** | 99 (54.396)*** | 48 (26.374)*** |
| H2O2+Que | 35 | 1 | 196 | 186 (94.898) ** | 150 (76.531)**, # | 118 (60.204)*** | 62(31.633)** |
| 35 | 5 | 191 | 189 (98.953) | 163 (85.340)### | 146 (76.440)### | 87(45.550)### | |
| 35 | 10 | 182 | 179 (98.352) | 152 (83.516)### | 144 (79.121)### | 64(35.165)* | |
Differences between the groups were calculated using the x 2-test. Que: quercetin.
* P<0.05, ** P<0.01, *** P<0.001 vs. the control group.
#
P<0.05, ## P<0.01, ### P<0.001 vs. the H2O2-treated group.