Table 2. EC50(Ca2+) values and Hill coefficients for interactions between CaM and GPER’s submembrane domains.* .
| Complexes | SMD | EC50(Ca2+)(µM) | Hill Coefficient |
| CaM-GPER83–93 (Species 1) | 1 | 0.13±0.02 | 1.99±0.14* |
| CaM-GPER83–93 (Species 2) | 1 | 3.71±0.13 | 2.53±0.15* ¶ |
| CaM-GPER150–175 | 2 | 2.38±0.13 | 1.21±0.09 |
| CaM-GPER242–259 | 3 | 5.15±0.55 | 1.43±0.11 |
| CaM-GPER330–351 | 4 | 0.75±0.05 | 1.18±0.08 |
Data are means ± SD of at least 3 independent determinations.
*All EC50(Ca2+) values are significantly different (p<0.05) from one another; Hill coefficients for GPER83–93sp1 and GPER83–93sp2 are different (p<0.05) from the rest.
¶, significantly different (p<0.05) from GPER83–93 (Species 1).