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. 2014 Feb 21;9(2):e89743. doi: 10.1371/journal.pone.0089743

Figure 4. The plasmalemmal repair of SLO pores occurs in lysosome-free cellular protrusions.

Figure 4

(A,B) SLO-induced plasmalemmal translocation/cytoplasmic back-translocation of annexin A1-YFP marks the successful elimination of the SLO-pores in (A) a neurite of a SH-SY5Y cell or in (B) a cytoplasmic protrusion of a HEK 293 cell. Arrows denote the plasmalemmal translocation of annexin A1 (plasmalemmal permeabilization). Magnified images of the squared region are shown in (A). Magnification bars = 5 µm.