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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: Chem Rev. 2013 Dec 5;114(1):233–254. doi: 10.1021/cr400161b

Figure 6.

Figure 6

Structure of the RXRα LBD tetramer in the absence of ligand.233 The four subunits are shown in different colors, but in each case helix-12 is in red. Helix-12 from each subunit traverses to the adjacent subunit to occupy the groove normally reserved for coactivator LLxxLL motif binding. Coordinates are from PDB ID 1G1U.