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. 2014 Feb 18;15:139. doi: 10.1186/1471-2164-15-139

Table 2.

List of consistently up- and downregulated transcripts (cut off 1.4 fold change)

  Gene Chromosome Function Protein levels Link to cancer?
1
PLAUR
19
Plasminogen activator, urokinase receptor
4/5
Ovarian and colorectal cancer
2
RAB27B
18
Secretory GTPase
4/4
Breast cancer
3
P4HA2
5
Procollagen-proline
4/6
Metastasis
4
FRY
13
Regulator of actin cytoskeleton
0/3
 
5
BDKRB1
14
Bradykinine receptor
NA
Breast and lung cancer
6
HOXB5
17
Transcription factor
NA
Leukemia, ovarian carcinoma and others
7
GDF15
19
Growth differentiation factor
1/2
Ovarian and prostate cancer
8
OASL
12
2'-5'-oligoadenylate synthetase-like
NA
 
9
SERPINE2
2
Serpine protease inhibitor
4/4
Metastasis
10
IFI44
1
Interferon-induced protein 44
NA
 
11
AMDHD1
12
Protein with amidohydrolase domain
NA
 
12
TMEM171
5
Transmembrane protein 171
NA
 
13
GLRX
5
Glutaredoxin
4/4
Pancreatic cancer
14
TMEM169
2
Transmembrane protein 169
NA
 
15
DMBT1
10
Membrane glycoprotein
NA
Multiple cancers
16
COL13A1
10
Collagen type XIII, alpha1
1/1
 
17
SH2D1B
1
Signal transduction control
NA
 
18
MIA
 
Melanoma inhibitory activity
NA
Neuronal tumors
 
 
 
 
 
 
1
XYLB
3
Xylulokinase homologue
NA
 
2
LOXL3
2
Lysyl oxidase homologue
NA
 
3
MYB/NFIB fusion
6
Myb – NFIB fusion
NA
 
4
EEPD
7
Endonuclease/exonuclease/phosphatase domain containing
NA
 
5 ARHGEF39 9 Rho guanine nucleotide exchange factor 39 NA  

The column “Protein levels” shows how often corresponding changes of the protein levels were identified by Stingele et al. [15] (number of cell lines with altered protein expression/number of cell lines where the protein was quantified; NA – proteomics data not available). The rows 1-18 show upregulated genes; the rows 1- 5 (below) show downregulated genes.