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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Curr Opin Immunol. 2013 Dec 22;0:140–146. doi: 10.1016/j.coi.2013.12.001

Figure 2.

Figure 2

Known and proposed functions of lncRNA in immunity. lncRNAs typically regulate transcription of a gene by forming complexes that bind a genomic region upstream of the transcription start site. lncRNA can potentially interact with other transcripts and regulate miRNA pathways, translation, splicing, and RNA turnover. lncRNAs with known molecular functions in immunity are colored black. Potential molecular functions for lncRNA in immunity are colored blue. Adapted from Hu et al [8]. lncRNA: long non-coding RNA, mRNA: messenger RNA, RNP: Ribonucleoprotein, hnRNPs: Heterogenous Ribonucleoproteins, NATs: Natural antisense transcripts.