Table 2.
Anatomical Distance Indices in the 3 Groups
| Scz | Sib | Con | t/χ 2 and F tests | |
|---|---|---|---|---|
| ADF | −0.5979 (0.0455) |
−0.5396 (0.0573) |
−0.4381 (0.0530) |
ANOVA: F = 98.71, P < .001 Con vs Scz: t = 13.7550, P < .001 Con vs Sib: t = 8.1550, P < .001 Sib vs Scz: t = 4.3170, P < .001 |
| MAD | 34.7333 (28.7373) |
44.3558 (33.1309) |
45.0083 (30.5165) |
ANOVA: F = 3.19, P = .043 Con vs Scz: t = 2.5025 P = .0130 Con vs Sib: t = 0.1518, P = 0.8794 Sib vs Scz: t = 1.9377, P = .0545 |
| S-long | −0.063 (0.032) |
−0.0187 (0.027) |
−0.0562 (0.023) |
ANOVA: F = 24.16, P < .001 Con vs Scz: t = 1.1534, P = .2519 Con vs Sib: t = −6.6623, P < .001 Sib vs Scz: t = 5.0871, P < .001 |
| S-short | 0.26 (0.0320) |
0.2795 (0.0450) |
0.1487 (0.0328) |
ANOVA: F = 166.79, P < .001 Con vs Scz: t = −14.9515, P < .001 Con vs Sib: t = −15.4335, P < .001 Sib vs Scz: t = 1.8361, P = .0774 |
| P-long vs P-short | 36% vs 64% | 40% vs 60% | 46% vs 54% | Con vs Scz: χ2 = 17.5569, P < .001 Con vs Sib: χ2 = 7.6874, P = .0056 Sib vs Scz: χ2 = 1.5110, P = .2090 |
Note: ADF, anatomical distance function; MAD, mean anatomical distance; S-long, connectivity strength of long-range connections; S-short, connectivity strength of short-range connections; P-long, proportion of all long-range connections; P-short, proportion of all short-range connections; Scz, patients with schizophrenia; Sib, healthy siblings of patients with schizophrenia; Con, healthy controls. Numbers in brackets represent the standard deviation.