Table 2. Incidence of frontotemporal dementia (FTD).
| Location/Study | Sampling Frame and method | Interval (Years) |
Sample | Age group |
Age at onset |
Sex ratio (M:F) |
N | Incidence | 95% CI |
|---|---|---|---|---|---|---|---|---|---|
| Rochester, USA (Knopman et al., 2004) |
City/suburban network; linked and coded records |
4 | FTD+PPA | 40–69 | 57.5 | 0:4 | 4 | 4.1 | 1.1–10.4 |
| Cambridgeshire, UK (Mercy et al., 2008) |
Regional network; coded records |
6 | FTD | 45–64 | 57 | 1.3:1 | 16 | 3.5 | 2.0–5.7 |
| Girona, Spain (Garre-Olmo et al., 2010) | Regional network; surveillance registry |
3 | FTD+PPA | 30–64 | NR | NR | 14 | 1.3 | 0.7–2.2 |
| 65+ | NR | 56 | 16.7 | 12.6–21.7 | |||||
| 45–64 | NR | 14 | 2.7 | 1.5–4.6* |
*
As computed and reported by Knopman and Roberts, 2011 (Knopman & Roberts, 2011).
Median age at onset calculated from data provided in the published reports.
NR = not reported.
FTD=frontotemporal dementia; PPA = primary progressive aphasia. Three studies report prevalence for subtypes of FTD.