Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Regulation of ROCK activation. (A) The catalytic domain of ROCK is located at the amino terminus, followed by a coiled-coil–forming region and a pleckstrin-homology (PH) domain with a cysteine-rich domain (CRD) at the carboxyl terminus. (B) Active Rho binds to the RBD domain of ROCK, resulting in an open conformation and thereby activation of the ROCK.
