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. Author manuscript; available in PMC: 2014 Dec 20.
Published in final edited form as: ACS Synth Biol. 2013 Aug 22;2(12):724–733. doi: 10.1021/sb400076r

Figure 2. SCHEMA disruption in chimeric VP capsids.

Figure 2

Capsid disruption (Ecapsid) was calculated for all chimeras that can be created by recombining AAV2 and AAV4 using (a) single and (b) double crossovers. Capsid disruption is shown relative to the per subunit amino acid substitution level (msubunit), which was calculated relative to AAV4 (m = 0).