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Relationship among p53 m RNA expression and p53 mutation in colorectal cancer patients n (percent)
| P53 mRNA expression | p | ||
|---|---|---|---|
| Negative expression | Positive expression | ||
| p53 mutation status | |||
| SSCP+M | 22 (75.9) | 7 (24.1) | <0.005 |
| SSCP–WT | 36 (26.1) | 102 (73.9) | |
SSCP+ positive mobility shift of p53 (p53 mutated profile), SSCP− negative mobility shift of p53 (p53 wild type)
