Table 2.
Select Demographic, Biochemical, and Chronic Liver Disease Questionnaire Scores in Cirrhotic Patients with and without Muscle Cramps
| Patients with Cramps (n = 101, 67%) | Patients without Cramps (n = 49, 33%) | P | |
|---|---|---|---|
| Mean age (± SD), y | 55 ± 10 | 57 ± 10 | .28 |
| Male (%) | 58 | 61 | .85 |
| Caucasian (%) | 79 | 78 | 1.0 |
| BMI (kg/m2) | 29 ± 7 | 29 ± 5 | .9 |
| Mean arterial pressure (mm Hg) | 91 ± 15 | 95 ± 11 | .11 |
| Proportion with hepatic encephalopathy (%) | 50 | 39 | .22 |
| Proportion with ascites (%) | 67 | 63 | .71 |
| Diuretic usage (%) | 66 | 54 | .12 |
| Serum total calcium, mg/dL (mean ± SD) | 8.9 ± 0.6 | 9.0 ± 0.6 | .16 |
| Serum albumin, g/dL (mean ± SD) | 3.1 ± 0.7 | 3.3 ± 0.7 | .04 |
| Serum sodium, mmol/L (mean ± SD) | 136 ± 5 | 137 ± 4 | .12 |
| Serum potassium, mmol/L (mean ± SD) | 4.0 ± 0.6 | 4.0 ± 0.5 | .30 |
| Serum creatinine, mg/dL (mean ± SD) | 1.0 ± 0.6 | 1.0 ± 0.5 | .88 |
| International normalized ratio | 1.4 ± 0.4 | 1.3 ± 0.3 | .05 |
| Child Pugh score (mean ± SD) | 8 ± 2 | 8 ± 2 | .9 |
| MELD score (mean ± SD) | 13.3 ± 5.7 | 12.1 ± 4.5 | .16 |
| 25-(OH) vitamin D (ng/mL) | 18.0 ± 8.9 | 19.6 ± 9.5 | .49 |
| CLDQ score (mean ± SD) | 107 ± 37 | 137 ± 34 | <.0001 |
| Abdominal symptoms | 12 ± 5 | 16 ± 5 | <.05 |
| Fatigue | 15 ± 7 | 20 ± 8 | <.0001 |
| Systemic symptoms | 20 ± 7 | 28 ± 6 | <.0001 |
| Activity | 12 ± 5 | 16 ± 5 | <.05 |
| Emotional function | 30 ± 12 | 37 ± 13 | <.01 |
| Worry | 19 ± 9 | 22 ± 9 | .06 |
SD = standard deviation; BMI = body mass index; MELD = Model for End-Stage Liver Disease; CLDQ = Chronic Liver Disease Questionnaire.