Table 3.
Variables Associated with Prevalence and Severity of Muscle Cramps and Quality of Life in Patients with Cirrhosis: Summary of Univariable and Multivariable Analysis
| Univariable Analysis
|
Multivariable Analysis
|
|||
|---|---|---|---|---|
| Odds Ratio (95% CI) | P | Odds Ratio (95% CI) | P | |
| Occurrence of cramps | ||||
| Albumin | 0.55 (0.32–0.95) | .03 | 0.62 (0.35–1.08) | .09 |
| INR | 2.93 (0.88–9.72) | .07 | 2.14 (0.62–7.38) | .23 |
| Severe cramps (CSS > 12) | ||||
| Age | 0.96 (0.93–1.0) | .03 | Not applicable | |
| CLDQ | Univariable Analysis
|
Multivariable Analysis
|
||
|---|---|---|---|---|
| Parameter Estimate | P | Parameter Estimate | P | |
| Serum albumin | 13.15 | .0048 | 3.69 | .51 |
| Hepatic encephalopathy | −19.30 | .0020 | −15.46 | .009 |
| Muscle cramps | −30.21 | <.0001 | −28.05 | <.001 |
| Serum total calcium | 12.88 | .0164 | 7.07 | .27 |
CSS = Composite Symptom Score; INR = international normalized ratio; CLDQ = Chronic Liver Disease Questionnaire.