Table 1.
Characteristics of the subjects, myosin heavy chain profiles, and variables of glucose metabolism.
| Characteristics | IGT | T2D | P value |
|---|---|---|---|
| n = (female/male) | 8 (4/4) | 10 (4/6) | |
| Age, year | 61.4 ± 2.8 | 62.5 ± 1.6 | 0.240 |
| BMI | 29.7 ± 0.9 | 29.0 ± 0.5 | 0.366 |
| VO2max, mL/kg−1/min−1 | 26.1 ± 2.8 | 26.5 ± 1.9 | 0.907 |
| Myosin heavy chain profile | |||
| MHC I, % | 37.3 ± 2.0 | 58.1 ± 5.0 | 0.001 |
| MHC IIa, % | 42.9 ± 2.8 | 34.8 ± 4.7 | 0.081 |
| MHC IIx, % | 19.8 ± 2.6 | 7.0 ± 2.1 | 0.009 |
| Blood chemistry | |||
| Fp-glucose, mmol/L | 5.6 ± 0.2 | 7.1 ± 0.3 | 0.004 |
| S-insulin, μU/mL | 15.4 ± 3.3 | 8.4 ± 0.5 | 0.009 |
| HbA1c, %* | 5.7 ± 0.2 | 6.4 ± 0.1 | 0.006 |
| HOMA-IR | 5.0 ± 0.9 | 2.7 ± 0.2 | 0.020 |
| HOMA-beta % | 50.2 ± 5.4 | 20.3 ± 1.4 | 0.001 |
Data are given as means ± SE.
*HbA1c values (in mmol) are 39 and 46 mmol/mol in the IGT and T2D groups respectively (IFCC-HbA1c).