Table 3.
Patient versus proxy comparison for baseline quality of life
| SF-36 domain | Na | Mean Patient estimate | Mean Proxy estimate | Mean paired difference [95% CI] (patient - proxy) | P-value for difference >0b | MCID (30) | P-value for Difference ≥ MCIDc |
|---|---|---|---|---|---|---|---|
| Physical Function | 136 | 69.6 | 63.4 | 6.2 [0.42, 12.0] | 0.036 | 10.0 | 0.903 |
| Physical Role | 135 | 64.0 | 56.7 | 7.3 [1.6, 13.0] | 0.012 | 12.5 | 0.964 |
| Bodily Pain | 133 | 62.8 | 56.1 | 6.7 [0.9, 12.4] | 0.023 | 10.0 | 0.875 |
| General Health | 133 | 56.4 | 45.1 | 11.2 [6.7, 15.8] | <0.001 | 10.0 | 0.294 |
| Vitality | 134 | 56.4 | 49.8 | 6.6 [2.0, 11.2] | 0.005 | 12.5 | 0.994 |
| Social Function | 134 | 68.5 | 61.2 | 7.3 [1.2, 13.4] | 0.020 | 12.5 | 0.954 |
| Emotional Role | 132 | 75.6 | 71.0 | 4.6 [−1.6, 10.8] | 0.140 | 8.3 | 0.880 |
| Mental Health | 133 | 68.8 | 63.3 | 5.5 [1.5, 9.4] | 0.007 | 10.0 | 0.987 |
Abbreviations: CI – confidence interval; MCID – minimal clinically important difference
a
When a domain could not be scored for either a patient or proxy, that specific domain was omitted from analysis
b
P-value for testing if the mean paired difference is greater than zero
c
P-value for testing if the mean paired difference is greater than or equal to the MCID (30)