Figure 2.
Specific activity of Av1 measured by the standard assay at pH 7.8 following incubation at pH 9.5 and 30 °C for the indicated times. The reactions at pH 9.5 were variations of the full turnover conditions with 0.25 mg of Av1: (●) Av1 and Av2 at a CR of 2.5 with the ATP regenerating system, (◆) Av1 and Av2 at a CR of 2.5 with the nonhydrolyzable ATP analogue AMP-PNP, (▲) Av1 with the ATP regenerating system (without Av2), and (■) Av1 and Av2 at a CR of 2.5 without nucleotide. Error bars indicate the standard deviation for duplicate experiments.