Table 5.
Outcomes Over Time by Treatment Group Adjusting for Baseline Value of Outcome and Current Chemotherapy
| Symptom Outcomes | Summary Statisticsa | Differences Between Groups | Repeated Measures Results | ||
|---|---|---|---|---|---|
| T2 Mean (SE) |
T3 Mean (SE) |
T2 Mean (SE) t-value(df) P-value |
T3 Mean (SE) t-value(df) P-value |
F-value (n,df) P-value |
|
| Severity | FGroup(1, 31.1)=1.50 P=0.229 |
||||
| WRITE Symptoms | 4.67 (0.43) | 4.58 (0.58) | −0.94 (0.48) t(40.4)=−1.95 P=0.058 |
−0.31 (0.64) t(47.3)=−0.49 P=0.626 |
FTime(1,50.1)=2.77 P=0.102 FG×T(1, 49.6)=1.72 |
| Control Group | 5.61 (0.22) | 4.80 (0.27) | P=0.196 | ||
| Distress | FGroup(1, 56.7)=4.59 P=0.037 |
||||
| WRITE Symptoms | 1.41 (0.13) | 1.42 (0.13) | −0.45 (0.17) t(88.4)=−2.57 P=0.012 |
−0.186 (0.17) t(87.8)=−1.09 P=0.281 |
FTime(1,55)=1.69 P=0.199 FG×T(1,54.1)=2.18 |
| Control Group | 1.85 (0.11) | 1.61 (0.11) | P=0.146 | ||
| Consequences | FGroup(1,57.4) =0.92 P=0.343 |
||||
| WRITE Symptoms | 1.77 (0.10) | 1.76 (0.10) | −0.164 (0.14) t(87.6)=−1.17 P=0.244 |
−0.180 (0.14) t(87.2)=−1.31 P=0.194 |
FTime(1,55.3)=0.86 P=0.357 FG×T(1,54.4)=0.51 |
| Control Group | 1.94 (0.09) | 1.82 (0.09) | P=0.480 | ||
| Controllability | FGroup(1, 50.8)=0.18 P=0.673 |
||||
| WRITE Symptoms | 2.19 (0.11) | 2.11 (0.10) | 0.120 (0.14) t(87.3)=0.84 P=0.404 |
−0.018 (0.14) t(86.7)=−0.13 P=0.898 |
FTime(1, 49.5)=0.02 P=0.891 FG×T(1,48.6)=0.84 |
| Control Group | 2.17 (0.09) | 2.13(0.09) | P=0.365 | ||
a
Values in cells are reported as least squares mean (standard error for mean) based on a linear mixed model adjusted for baseline level of outcome and whether on current chemotherapy.