Systemic AMPH (1 mg/kg i.p.) administration caused a significant rise in locomotor activity compared to a group which received AMPH (1 mg/kg i.p.) in addition to VL perfusion of TTX (10 μM; black bar). Data are expressed as locomotor counts ± SEM.
*p<0.05, AMPH-only time point significantly different from AMPH + TTX treated group
**p<0.01, AMPH-only time point significantly different from AMPH + TTX treated group