Table 2. Baseline values and 6-month Changes in blood pressure in 109 patients.

Variable	Systolic pressure	Diastolic pressure
Office, mm Hg
BL	174.5±25.7	98.0±18.6
Δu	−17.6 (−22.0 to −13.1)‡	−7.1 (−9.8 to −4.5)‡
Δa	−14.2 (−17.7 to −10.6)‡	−6.5 (−8.8 to −4.2)‡
24-h, mm Hg
BL	156.7±17.4	91.5±14.2
Δu	−5.9 (−9.0 to −2.8)‡	−3.5 (−5.5 to −1.5)‡
Δa	−5.2 (−7.9 to −2.6)‡	−3.1 (−4.7 to −1.4)‡
Daytime, mm Hg
BL	160.8±18.0	94.9±15.3
Δu	−6.2 (−9.5 to −2.9)†	−3.4 (−5.5 to −1.4)‡
Δa	−5.6 (−8.3 to −2.8)‡	−3.3 (−5.1 to −1.5)‡
Nighttime, mm Hg
BL	147.0±20.8	83.5±15.1
Δu	−4.4 (−7.9 to −1.0)*	−2.5 (−4.8 to −0.2)*
Δa	−4.9 (−7.7 to −2.1)‡	−2.3 (−4.1 to −0.5)*
Office minus 24-h, mm Hg
BL	18.2±22.5	6.7±13.4
Δu	−12.0 (−16.4 to −7.7)‡	−3.7 (−6.2 to −1.3)†
Δa	−7.7 (−10.7 to −4.6)‡	−2.6 (−4.6 to −0.7)†
Office minus daytime, mm Hg
BL	14.0±22.6	3.3±14.1
Δu	−11.8 (−16.2 to −7.4)‡	−3.7 (−6.2 to −1.3)†
Δa	−8.4 (−11.7 to −5.1)‡	−2.6 (−4.6 to −0.6)*

BL, Δu and Δa respectively indicate baseline value, unadjusted change (follow-up minus baseline), and change estimates derived from mixed models, while adjusting for baseline as fixed effect and center as random effect. Baseline values are mean±s.d. Changes are crude or adjusted means with 95% confidence interval. Office minus 24-h or daytime blood pressure is a measure for the white-coat effect.

Significance of the changes: *P⩽0.05; †P⩽0.01; ‡P⩽0.001.