Table 4. Baseline predictors of the 6-month responses of office and 24-h systolic blood pressures to renal denervation in 109 patients.
Blood pressure control | Improved blood pressure control | No decrease in blood pressure | |
---|---|---|---|
Office blood pressure, mm Hg | |||
Number of patients in category (%) | 25 (22.9) | 65 (59.6) | 25 (22.9) |
Baseline (+10 mm Hg) | 0.78 (0.61–0.99)† | 1.36 (1.10–1.69)‡ | 0.71 (0.54–0.93)‡ |
Being female (0,1) | 1.12 (0.30–4.00) | 1.00 (0.31–3.28) | 1.41 (0.33–5.99) |
Age (+10 years) | 0.81 (0.52–1.27) | 0.72 (0.47–1.10) | 1.36 (0.85–2.16) |
Body mass index (+5 kg m−2) | 0.62 (0.34–1.14) | 1.20 (0.70–2.07) | 0.62 (0.31–1.25) |
Serum creatinine (+20 μmol l−1) | 1.01 (0.66–1.54) | 0.61 (0.39–0.97)† | 1.80 (1.11–2.91)† |
Having diabetes (0,1) | 2.19 (0.64–7.49) | 1.38 (0.42–4.53) | 0.46 (0.11–1.97) |
Cardiovascular disease (0, 1) | 1.08 (0.29–3.95) | 5.39 (1.41–20.6)† | 0.59 (0.14–2.56) |
24-h blood pressure, mm Hg | |||
Number of patients in category (%) | 16 (14.7) | 34 (31.2) | 38 (34.9) |
Baseline (+10 mm Hg) | 0.49 (0.39–0.79)‡ | 1.31 (0.99–1.73)* | 0.90 (0.69–1.17) |
Being female (0,1) | 0.73 (0.15–3.55) | 0.52 (0.17–1.64) | 1.80 (0.59–5.55) |
Age (+10 years) | 0.78 (0.44–1.40) | 1.35 (0.88–2.07) | 0.68 (0.45–1.03)* |
Body mass index (+5 kg m−2) | 0.72 (0.36–1.47) | 0.66 (0.40–1.09)* | 1.19 (0.73–1.94) |
Serum creatinine (+20 μmol l−1) | 0.53 (0.26–1.09)* | 0.60 (0.36–1.00)† | 1.66 (1.11–2.49)‡ |
Having diabetes (0,1) | 1.27 (0.28–5.72) | 1.43 (0.45–4.56) | 1.36 (0.46–4.04) |
Cardiovascular disease (0, 1) | 3.39 (0.69–16.7) | 0.49 (0.14–1.70) | 0.60 (0.18–1.96) |
Values are independent odds ratios with 95% confidence interval. All estimates were adjusted for the baseline systolic blood pressure and for all other predictors considered (see Table 3). Reaching control was achieving a systolic pressure <140 mm Hg or <130 mm Hg on office or 24-h ambulatory measurement, respectively. Reaching improved control was a decrease in the office or 24-h systolic pressure by ⩾10 mm Hg. No decrease was a systolic pressure at 6 months equal to or higher than the baseline value.
Significance of the odds ratios: *P⩽0.10; †P⩽0.05; ‡P⩽0.01.