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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Curr Allergy Asthma Rep. 2014 Feb;14(2):402. doi: 10.1007/s11882-013-0402-8

Table 2.

Clinical trial investigations utilizing FTY720

Clinical trial investigations of FTY720 No. of Studies Key references

Autoimmune and inflammatory fiseases 46 Kappos 2006 [136]
 Multiple sclerosis Kappos 2010 [137]
  Primary progressive 2 Comi 2010 [138]
  Relapsing, remitting 22 O’Connor 2010 [139]
  Non-specified 18
 Chronic inflammatory demyelinating polyradiculoneuropathy 1 Kurose 2000a [140]
Commodaro 2009a [141]
Copland 2012a [142]
Zhang 2009a [143]
Sawicka 2003a [144]
 Uveitis 1
 Acute demyelinating optic neuritis 1
 Asthma 1

Neurological disease/disorder 2
 Amyotrophic lateral sclerosis 1 ClinicalTrials.gov
 Schizophrenia 1

Kidney Disease 11
 Transplantation 10 Budde 2002 [145]
 Renal insufficiency 1

Other 1
 Cardiac/pulmonary function 1 Schmouder 2012 [146]

Classified by condition-descriptions from ClinicalTrials.gov. Reference list is not exhaustive. References include published clinical trial results, if currently available

a

Indicates pre-clinical reference.