Table 1.

Characteristics of datasets and gold standard by adverse event

Event	No. patients in STRIDE	No. patients in PAMF	No. positive test cases
Total	565 998	969 511	849
Cardiac arrhythmias	88 555	109 601	65
Acute renal failure	32 197	28 994	15
Bradycardia	22 906	24 162	52
Hyperglycemia	19 189	41 574	47
Neutropenia	14 322	6783	13
Hypoglycemia	11 150	28 320	43
Pancytopenia	8718	2850	2
Hypokalemia	8405	10 356	44
Hyperkalemia	4973	7691	142
Parkinsonian symptoms	3541	4605	9
Nephrotoxicity	1460	639	83
Rhabdomyolysis	1378	1948	30
QT prolongation	1260	1441	150
Serotonin syndrome	674	1511	154

We consider 14 adverse events for our study; our gold standard contains a total of 849 positive test cases and 849 randomly generated negative test cases.

PAMF, Palo Alto Medical Foundation; STRIDE, Stanford Translational Research Integrated Database Environment.