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. Author manuscript; available in PMC: 2014 Feb 24.
Published in final edited form as: Am J Cardiol. 2012 Nov 17;111(3):374–381. doi: 10.1016/j.amjcard.2012.10.015

Figure 2.

Figure 2

Aortic stenosis (AS) severity and biomarkers plotted in 66 AS patients (closed circles) and 21 aortic valve replacement patients (open circles). Cutoff gradient values are dashed lines for severe AS (>40 mm Hg) and moderate AS (25-40 mm Hg). Blue circles indicate patients with no loss of high-molecular-weight multimer (HMWM) and red circles indicate HMWM loss. A, von Willebrand factor multimer (VWF:mult) ratio. B, Platelet function analyzer collagen plus adenosine diphosphate (PFA-CADP) closure time. C, Ratio of von Willebrand factor latex agglutination immunoturbidic activity to von Willibrand factor antigen (VWF:Ltx/VWF:Ag). D, Brain nutriuretic peptide (BNP) level plotted on a base 2 log scale.