Genotype differences in beam walk performance. (A) Ephx2-KO mice showed improved ability in the beam walk task during training, before surgery/injury. (B) Difference in beam walk latency 3 days after surgery (Δ = post − pre). As expected from the genotype effect before surgery, both sham and brain-injured Ephx2-KO mice showed better latencies than respective wild-type mice (sham: 4.70±0.92 s vs. 6.74±0.80 s, p<0.05;TBI: 5.80±0.87 s vs. 8.64±0.79 s, p<0.03). Results are mean ± standard error, with n = 20 for training, and n = 10 animals per post-surgery group. *p<0.05, Tukey HSD; §p<0.10, Genotype•Treatment effect, Tukey HSD.