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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Virology. 2013 Dec 20;449:304–316. doi: 10.1016/j.virol.2013.10.038

Table 1.

Summary of neutralization assay titers against HPV16 comparing the conventional HPV16 PsV neutralization assay and using fcPsV in FD11 cells.

Serum/monoclonal antibody used (replicates) 293TT assay neutralization titers (mean) FD11 assay neutralization titers (mean) Approximate fold change P-value
L2α(11-88)×5 (n=8) 788 8150 10 0.0078
L2α(11-88)×8 (n=10) 1270 9480 11 0.0156
Mouse monoclonal antibody, RG-1 (n=10) 320 88320 276 0.0020
Rat monoclonal antibody, WW1 (n=10) 70 76800 1097 0.0020
Cervarix™ (n=10) 228280 143360 −1.5 0.1055

Mean neutralization titers based on the reciprocal of the dilution that causes 50% reduction in luciferase activity is recorded. P-value is based on Wilcoxon matched-pairs signed rank test.