Table 5.
Expression fold changes of antioxidant and oxidative stress pathway genes in microarray data for rsh and msd mice.
| Gene | Expression Fold-Change Compared to Controls | ||||
|---|---|---|---|---|---|
| Microarrays | Taqman PCR | ||||
| rsh | msd | rsh | msd | ||
| Nfe2l2 | 1.03 ± 0.19 | 1.15 ± 0.13 | 1.53 ± 0.12 b | 1.5 ± 0.08 b | |
| Tfb2m | 1.02 ± 0.12 | 0.99 ± 0.15 | n.m. | n.m. | |
| Tfam | 1.13 ± 0.03 | 1.14 ± 0.07 | n.m. | n.m. | |
| MafF | 1.11 ± 0.15 | 1.21 ± 0.16 | n.m. | n.m. | |
| Sesn2 | 2.85 ± 0.42 a | 2.56 ± 0.51 a | n.m. | n.m. | |
| Prdx6 | 1.1 ± 0.25 | 1.50 ± 0.28 a | n.m. | n.m. | |
| Gpx | 1.24 ± 0.24 | 1.57 ± 0.40 a | n.m. | n.m. | |
| RelA | 1.06 ± 0.14 | 1.03 ± 0.10 | 1.61 ± 0.05 b | 1.04 ± 0.10 | |
| Sod1 | 1.06 ± 0.23 | 1.15 ± 0.24 | n.m. | n.m. | |
| Sod2 | 1.02 ± 0.19 | 1.01 ± 0.16 | n.m. | n.m. | |
| Cat | 0.81 ± 0.17 | 0.91 ± 0.12 | n.m. | n.m. | |
a fold change ≥ 1.5 and FDR < 0.1; b fold change ≥ 1.5 and p < 0.05; n.m., not measured.