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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Lancet Diabetes Endocrinol. 2014 Jan;2(1):38–45. doi: 10.1016/S2213-8587(13)70070-6

Table 3. Predictors of early and late T2D remission after RYGB surgery for patients using insulin (T2D+I) preoperatively.

Early remission (partial + complete) was defined by reaching diabetes-free status during the first two months after surgery and late remission (partial + complete) was defined by reaching diabetes-free status more than two months after surgery. In univariate analysis for early remission, there were 26 variables with p-value < 0·10 (14 with p-values < 0·05). In univariate analysis for late remission, there were 33 variables with p-value < 0·10 (17 with p-values < 0·05). Individual variables were added until the models below were developed. (% EWL: percent excess body weight loss).

Early T2D remission
Odds ratio 95% Confidence interval p-value

Age (years) Each 10 year decrease 2·21 [1·32, 3·70] 0·0024

Pre-operative HbA1c (%) <6·5 6·81 [1·95, 23·86] 0·027
6·5–6·9 3·20 [0·73, 13·98] 0·122
7·0–8·9 1·27 [0·37, 4·44] 0·706
9·0+ Reference - -

Hypertension diagnosis Yes 0·40 [0·16, 0·99] 0·046
No Reference - -

Use of incretin mimetic agent Yes 3·61 [1·08, 12·14] 0·038
No Reference - -

Late T2D remission
Hazard ratio 95% Confidence interval p-value

Post-op % EWL Each 10% increase 1·16 [1·05, 1·29] 0·0029

Age (years) Each 10 year decrease 1·79 [1·20, 2·63] 0·0036

Pre-operative HbA1c (%) <6·5 3·31 [1·19, 9·18] 0·022
6·5–6·9 1·67 [0·42, 6·75] 0·469
7·0–8·9 1·97 [0·81, 4·83] 0·137
9·0+ Reference - -