Table 1.
Transplant type | Total endocardial contribution | Atrial endocardial contribution | Ventricular endocardial contribution | Endothelial contribution | Myocardial contribution |
---|---|---|---|---|---|
WT to WT | 15/184 (8.2%) | 10/15 (66.7%) | 9/15 (60.0%) | 134/184 (72.8%) | 37/214 (17.3%) |
tal1 MO to WT | 21/299 (7.0%) | 2/21 (9.5%)* | 19/21 (90.5%) | 103/299 (34.4%)* | 52/451 (11.5%) |
WT to tal1 MO | 9/238 (3.8%) | 8/9 (88.9%) | 2/9 (22.2%) | 185/238 (77.7%) |
Each fraction reports the number of embryos in which donor cells contributed to a particular tissue divided by the total number of mosaic embryos scored. The fractions representing atrial and ventricular endocardial contributions indicate the number of embryos in which donor cells contributed to the atrial or ventricular endocardium divided by the total number of embryos displaying donor contribution to the endocardium. In some cases, donor cells contributed to both the ventricular and atrial endocardium (Fig. 2O). Asterisks indicate statistically significant differences from control transplants (wild-type into wild-type), as determined by Fisher’s exact test (p < .05).