Structural overview of the NTD of ctNup192. (A) Domain structure of ctNup192 (crystallized fragment is indicated by a black bar). The N-terminal Head module (yellow), HEAT module (green), hinge module (red), ARM module (blue), and CTD (gray) are indicated. (B) Structure of ctNup192NTD shown in a cartoon representation using the same coloring scheme as in A. The hinge and α31–α32 loops, which line the inner arch of the ring, are colored in red and orange, respectively. Dashed lines indicate disordered loops.