Fig. 4.

Robust IDUA levels were found in mpMPs that heterogeneously expressed Annexin V. (A) Representative FACS plots using MPs isolated from fresh whole blood after staining with CD41-PE and Annexin V–APC. The FSC and SSC characteristics of standard beads (0.5 and 1 µm) (Upper) were used for MP gating (Left and Center of the lower row). (B) Percentage of CD41⁺ MPs in isolates with Annexin V status. Data were derived from three independent assays (error bars: SD). (C) IDUA activity in isolated MPs (n = 7−10). UD, undetectable.