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Bioassay data after preparative HPLC fractionation of the 20% MeOH SPE fraction from bge080.
| Fractiona | Fraction weight (mg) |
MIC (µg/mL)a | IC50 (µg/mL)a |
SI | ||
|---|---|---|---|---|---|---|
| Mtb | NRP Mtb | Vero | Mtb | NRP Mtb |
||
| A | 91.74 | > 10 (2%) | > 10 (11%) | > 10 (13%) | NA | NA |
| B | 0.29 | > 10 (0%) | > 10 (35%) | > 10 (0%) | NA | NA |
| C | 5.21 | 1.18 | 0.49 | > 10 (36%) | > 8.47 | > 20.41 |
| D | 1.22 | 0.06 | < 0.039 | 1.44 | 24.00 | 36.92 |
| E | 4.44 | 4.06 | 1.49 | 8.66 | 2.13 | 5.81 |
All preparative HPLC fractions (codified A to E) were tested at 10 µg/mL.
