. Author manuscript; available in PMC: 2014 Feb 24.

Published in final edited form as: J Biol Chem. 2007 Dec 4;283(6):3487–3496. doi: 10.1074/jbc.M707630200

TABLE 5. CYP2E1 binding parameters for 4MP and IND.

4MP was fit to a two binding site model, whereas IND was fit to the single site model (Scheme 3). The nonsymmetrical 95% confidence intervals for the parameters are shown in parentheses.

Ligand	K_d₁	ε_1(430–392)	K_d₂	ε_2(430–392)
	μM	cm⁻¹ μM⁻¹	μM	cm⁻¹ μM⁻¹
4MP	0.67 (0.50–0.95)	0.045 (0.034–0.052)	1.3 (0.53–3.9)	0.039 (0.038–0.41)
IND	0.0052 (0.0028–0.0084)	0.030 (0.029–0.030)