Table 1.
BL | Control | Insulin | P | 2 h | Control | Insulin | P |
---|---|---|---|---|---|---|---|
HR (min−1) | 98.4 (8.6) | 107.9 (7.4) | 0.42 | HR (min−1) | 116 (6.8) | 113.4 (11.0) | 0.774 |
MAP (mmHg) | 85 (6.4) | 65.9 (3.9) | 0.03 | MAP (mmHg) | 69.4 (5.6) | 67.6 (2.0) | 0.973 |
MAWP (cm H2O) | 9.8 (0.5) | 10.0 (0.6) | 0.77 | MAWP (cm H2O) | 11.7 (0.8) | 11.0 (1.2) | 0.575 |
PIP (cm H2O) | 19.3 (1.6) | 19.4 (1.7) | 0.95 | PIP (cm H2O) | 26.1 (2.6) | 25.3 (2.6) | 0.816 |
PaO2/FiO2 | 445.6/45.9 | 438.4/14.0 | 0.87 | PaO2/FiO2 | 283.8/86.9 | 355/57.6 | 0.47 |
Shunt fraction | 11.9 (2.0) | 12.5 (0.7) | 0.76 | Shunt fraction | 18.5 (3.8) | 15.7 (2.3) | 0.464 |
Physiological parameters (means ± SEM) measured as a function of group at baseline and 2 h
BL baseline, HR heart rate, MAP mean arterial pressure, MAWP mean airway pressure, PIP peak inspiratory pressure, P is the P value to compare baseline-adjusted mean hemodynamics between control and insulin group