Table 4.
Biological process (BP) terms and annotation clusters significantly down-regulated due to the main effect of age
| Cluster | Description | N | X 2 adj A | Orthologues B |
|---|---|---|---|---|
| GO:0005524 |
ATP binding (MF) |
10 |
0.0029 |
FBgn0260990, FBgn0261014, FBgn0032243, FBgn0025743, FBgn0026059, FBgn0000723, FBgn0030343, FBgn0015615, FBgn0036486, FBgn0051729 |
| Kegg:03040 |
Spliceosome |
3 |
0.0099 |
FBgn0031390, FBgn0038927, FBgn0031266 |
| GO:0007391 |
Dorsal closure (BP)C |
3 |
0.0048 |
FBgn0010434, FBgn0000723, FBgn0044323 |
| IPR001680, IPR011046, IPR019775 |
WD40 repeat, WD40 repeat-like-containing domain, WD40 repeat, conserved site |
5 |
<0.0001 |
FBgn0037758, FBgn0029903, FBgn0044323, FBgn0038927, FBgn0043362 |
| IPR001680, IPR011046, IPR019775, IPR020472, IPR019782, IPR017986, IPR019781 |
WD40 repeat, WD40 repeat-like-containing domain, WD40 repeat, conserved site, G-protein beta WD-40 repeat, WD40 repeat 2, WD40-repeat-containing domain, WD40 repeat, subgroup |
4 |
<0.0001 |
FBgn0029903, FBgn0044323, FBgn0038927, FBgn0043362 |
| IPR011046 |
WD40 repeat-like-containing domain |
6 |
<0.0001 |
FBgn0037758, FBgn0029903, FBgn0024698, FBgn0044323, FBgn0038927, FBgn0043362 |
| GO:0003779 |
Actin binding (MF) |
3 |
0.0109 |
FBgn0035347, FBgn0010434, FBgn0029903 |
| IPR016024 |
Armadillo-type fold |
4 |
0.0248 |
FBgn0260990, FBgn0030674, FBgn0043362, FBgn0031266 |
| GO:0016319 |
Mushroom body developmentD |
2 |
0.0071 |
FBgn0025743, FBgn0010051 |
| GO:0007030 | Golgi organizationD | 2 | 0.0019 | FBgn0261014, FBgn0033075 |
AX2adj refers to the significance of the Fisher’s exact test with a Benjamini-Hochberg correction for multiple comparisons.
BOrthologues represent Drosophila melanogaster genes similar to the differentially expressed transcripts discovered in the present study that are listed in FlyBase.
CTerms that were significant BP terms and were part of a significant gene annotation cluster.
DTerms that represented significant BP terms but did not form a significant gene annotation cluster.