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Tumor-infiltrating lymphocytes (TILs) changes before and after neoadjuvant chemotherapy. Intratumoral-TIL (It-TIL, A) and stromal-TIL (Str-TIL, B) level changes from diagnostic core biopsy (prechemotherapy) to surgical specimen (postchemotherapy) for patients having a High-TIL residual disease after neoadjuvant chemotherapy. Illustration of a case changing from Low-TIL (core biopsy, C) to High-TIL (residual disease, D).
