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. Author manuscript; available in PMC: 2014 Dec 12.
Published in final edited form as: J Med Chem. 2013 Nov 23;56(23):9756–9770. doi: 10.1021/jm401468w

Table 2.

Antibacterial Activity of Benzimidazoles 6 Against Mtb H37Rv Strain (MIC, µg/mL) and Their Cytotoxicity (IC50, µg/mL)

Compound R1R2N R3NH Mtb H37Rv
MIC
Vera
Cytotoxicity
6a graphic file with name nihms544122t35.jpg graphic file with name nihms544122t36.jpg >100 >100
6b graphic file with name nihms544122t37.jpg graphic file with name nihms544122t38.jpg >100 >100
6c graphic file with name nihms544122t39.jpg graphic file with name nihms544122t40.jpg >100 >100
6d graphic file with name nihms544122t41.jpg graphic file with name nihms544122t42.jpg 25.0 >100
6e graphic file with name nihms544122t43.jpg graphic file with name nihms544122t44.jpg 25.0 >100
6f graphic file with name nihms544122t45.jpg graphic file with name nihms544122t46.jpg 100 >100
6g graphic file with name nihms544122t47.jpg graphic file with name nihms544122t48.jpg 6.25 >100