Figure 1. The antimycin biosynthetic gene cluster in Streptomyces albus S4.

Genes shaded grey indicate those that are required for antimycin biosynthesis. Genes shaded black were experimentally determined not to be required for antimycin biosynthesis. Narrow black arrows indicate the presence of four operons and the direction of their transcription. The locations of cosmid 213 and cosmid 456 are indicated by horizontal lines and the double vertical hash indicates that cosmid 456 is comprised of additional DNA that falls outside the boundaries of this schematic.