Table 2. Biochemical data of the KPE19 volunteer cohort.

		Mean ±SD	Median (25–75% percentile)
Plasma (µmol/L) *	SDMA	0.42±0.07	0.41 (0.37–0.45)
	ADMA	0.38±0.07	0.37 (0.34–0.42)
	L-arginine	83.2±40.1	73.1 (57.7–98.4)
	BAIB	1.09±0.42	1.02 (0.80–1.21)
Urine (µmol/g creatinine) †	SDMA	37.0±7.8	36.4 (31.7–42.1)
	ADMA	33.3±9.2	31.6 (27.1–37.7)
	L-arginine	16.0±9.3	13.9 (10.8–18.6 )
	BAIB	90.1±130	54.0 (33.7–93.4)
Creatinine	Serum (mg/dL) ‡	0.8±0.1	0.8 (0.7–0.9)
	Urine (mg/dL) †	104±84	86 (37–144)
	Clearance (ml/min) ‡ §	127±28	123 (109–142)

Plasma and urinary concentrations were measured by HPLC-MS/MS.

* Plasma concentrations were determined for 395 volunteers.

^†Urinary concentrations were measured for 400 volunteers.

^‡Serum creatinine concentrations and creatinine clearance were determined for 390 volunteers.

^§Cockcroft-Gault formula was used for calculation of creatinine clearance.