Table 2. Drug susceptibility of rtM204Q and rtM204I mutants and wild-type strain.

	Wild-type		rtM204Q		rtM204I
	EC50	fold	EC50	fold	EC50	fold
Lamivudine	0.158±0.012	1.00	11.96±2.36	75.68	220.50±29.85	1395.57
Adefovir	0.089±0.008	1.00	0.168±0.092	1.89	0.085±0.021	0.96
Entecavir	0.00196±0.0002	1.00	0.00033±0.00009	0.17	0.0068±0.0009	3.47
Tenofovir	0.024±0.005	1.00	0.113±0.020	4.69	0.072±0.008	2.98

EC₅₀, 50% effective concentration of drug (µ mol/L).