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. 2014 Feb 17;6:93–100. doi: 10.2147/CEOR.S54797

Table 1.

Patient characteristics according to treatment3

France
Spain
UK
All patients
(n=1,374)
Biologic treatment
(n=125)
Nonbiologic treatment
(n=1,249)
P-valueb All patients
(n=561)
Biologic treatment
(n=109)
Nonbiologic treatment
(n=452)
P-valueb All patients
(n=574)
Biologic treatment
(n=48)
Nonbiologic treatment
(n=526)
P-valueb
Mean age, years 46.6 50.4 46.3 0.0005 42.4 42.8 42.3 0.77 43.9 44.3 43.8 0.82
Male 769 (56.0%) 78 (62.4%) 691 (55.3%) 0.13 329 (58.7%) 71 (65.1%) 258 (57.1%) 0.12 301 (52.4%) 25 (52.1%) 276 (52.5%) 0.96
Mean length of diagnosis, years 9.2 15.0 8.6 <0.0001 9.5 11.8 8.8 0.0186 12.4 14.8 12.2 0.16
BMI ≥30c 135 (9.8%) 26 (21.0%) 109 (8.7%) <0.0001 52 (9.3%) 18 (16.5%) 34 (7.6%) 0.003 86 (15.0%) 14 (29.2%) 72 (13.7%) 0.2
Mean PASI scored 9.9 14.7 9.4 <0.0001 9.6 12.9 8.6 0.0005 10.4 13.0 10.2 0.10
Nail involvement 355 (25.8%) 60 (48.0%) 295 (23.6%) <0.000l 165 (29.4%) 53 (48.6%) 112(24.8%) <0.0001 244 (42.5%) 24 (50.0%) 220 (41.8%) 0.27
Psoriatic arthritise 127(9.2%) 44 (35.2%) 83 (6.6%) <0.000l 35 (6.2%) 17 (15.6%) 18 (3.9%) <0.0001 75 (13.0%) 22 (45.8%) 53 (10.0%) <0.000l

Notes:

a

A total of 79 patients were excluded from 2,588 patients; all values are percentages unless otherwise indicated;

b

P-values are for the comparison between biologic users and nonusers in each country;

c

BMI data were available for only 1,369 patients from France, 557 patients from Spain, and 360 patients from the UK;

d

mean PASI scores were calculated from measured or imputed data for 1,270, 481, and 538 patients from France, Spain, and the UK, respectively;

e

psoriatic arthritis was reported for only 1,374 patients from France, 546 patients from Spain, and 570 patients from the UK.

Abbreviations: BMI, body mass index; CI, confidence interval; PASI, Psoriasis Area and Severity Index.