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. 2014 Feb 20;14:111. doi: 10.1186/1471-2407-14-111

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Copyright © 2014 Pentheroudakis et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Gene clustering in microarray analysis of test set according to 8-month progression-free endpoint. Hierarchical clustering was performed using the euclidean distance and the average linkage algorithm. UPPER ROW-PD8m: Progressive disease during first 8 months from treatment start, noPD8m: Progression-free during 8 months from treatment start. LOWER ROW- Patient tumor samples (n = 16, two patients ineligible). VERTICAL LEFT: Expression of five genes. Red denotes overexpression, Green denotes underexpression.