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. 2014 Feb 20;9:27. doi: 10.1186/1750-1172-9-27

Table 1.

Associations between predictor variables and case/control status

Characteristics
 
TOF (N=404)
Controls (N=4 250)
p
    n* % § n* % §  
Mother
Age (years)
 
 
 
 
 
 
Mean (SD)
31.7 (5.6)
30.4 (5.2)
<0.001
 
Median (p25-p75)
31.5 (28 – 36)
30 (27 – 34)
 
 
<20
3
0.8
59
1.4
<0.001
 
20 – 29
146
36.5
1,809
42.8
 
30 – 34
126
31.5
1,434
33.9
 
35 – 39
91
22.8
722
17.1
 
≥ 40
34
8.5
203
4.8
 
Geographic origin
 
 
 
 
 
 
France
200
50.4
2,412
57.9
<0.001
 
North Africa
72
18.1
433
10.4
 
Subsaharan Africa
39
9.8
550
13.2
 
Other
86
21.7
770
18.5
 
Occupation
 
 
 
 
 
 
None
113
30.9
1,083
26.3
0.096
 
Professional
84
23.0
997
24.2
 
Intermediate
64
17.5
856
20.8
 
Administrative/public service
67
18.3
852
20.7
 
Other
38
10.4
330
8.0
Father
Age (years)
 
 
 
 
 
 
Mean (SD)
35.0 (6.6)
33.9 (6.6)
0.006
 
Median (p25-p75)
34 (30 – 39)
33 (29 – 38)
 
 
<20
1
0.3
5
0.1
0.014
 
20 – 29
59
19.5
890
25.8
 
30 – 34
94
31.1
1,198
34.7
 
35 – 39
79
26.2
734
21.3
 
≥ 40
69
22.9
734
21.3
 
Geographic origin
 
 
 
 
 
 
France
179
49.2
2,325
58.6
<0.001
 
North Africa
66
18.1
416
10.5
 
Subsaharan Africa
38
10.4
529
13.3
 
Other
81
22.3
700
17.6
 
Occupation
 
 
 
 
 
 
None
24
7.6
281
7.4
0.014
 
Professional
110
34.6
1,474
38.6
 
Intermediate
44
13.8
566
14.8
 
Administrative/public service
28
8.8
479
12.5
 
Other
112
35.2
1,020
26.7
Pregnancy
Outcome
 
 
 
 
 
 
Still-births
18
4.5
7
0.2
<0.001
 
Live-births
269
66.6
4,231
99.6
 
Pregnancy terminations
117
29.0
12
0.3
Art
None
369
93.4
3,959
96.5
0.004
 
IO$ only
11
2.8
77
1.9
 
IVF£ only
10
2.5
55
1.3
  IVF+ICSI¥ 5 1.3 13 0.3  

*n represents the number of cases or controls without missing data.

§% calculated with the number of cases or controls without missing data as a denominator.

$Inductors of ovulation.

£In vitro fertilization.

¥IVF with intracytoplasmic sperm injection.