Table 1.
Characteristics |
|
TOF (N=404) |
Controls (N=4 250) |
p |
||
---|---|---|---|---|---|---|
n* | % § | n* | % § | |||
Mother |
Age (years) |
|
|
|
|
|
|
Mean (SD) |
31.7 (5.6) |
30.4 (5.2) |
<0.001 |
||
|
Median (p25-p75) |
31.5 (28 – 36) |
30 (27 – 34) |
|
||
|
<20 |
3 |
0.8 |
59 |
1.4 |
<0.001 |
|
20 – 29 |
146 |
36.5 |
1,809 |
42.8 |
|
|
30 – 34 |
126 |
31.5 |
1,434 |
33.9 |
|
|
35 – 39 |
91 |
22.8 |
722 |
17.1 |
|
|
≥ 40 |
34 |
8.5 |
203 |
4.8 |
|
|
Geographic origin |
|
|
|
|
|
|
France |
200 |
50.4 |
2,412 |
57.9 |
<0.001 |
|
North Africa |
72 |
18.1 |
433 |
10.4 |
|
|
Subsaharan Africa |
39 |
9.8 |
550 |
13.2 |
|
|
Other |
86 |
21.7 |
770 |
18.5 |
|
|
Occupation |
|
|
|
|
|
|
None |
113 |
30.9 |
1,083 |
26.3 |
0.096 |
|
Professional |
84 |
23.0 |
997 |
24.2 |
|
|
Intermediate |
64 |
17.5 |
856 |
20.8 |
|
|
Administrative/public service |
67 |
18.3 |
852 |
20.7 |
|
|
Other |
38 |
10.4 |
330 |
8.0 |
|
Father |
Age (years) |
|
|
|
|
|
|
Mean (SD) |
35.0 (6.6) |
33.9 (6.6) |
0.006 |
||
|
Median (p25-p75) |
34 (30 – 39) |
33 (29 – 38) |
|
||
|
<20 |
1 |
0.3 |
5 |
0.1 |
0.014 |
|
20 – 29 |
59 |
19.5 |
890 |
25.8 |
|
|
30 – 34 |
94 |
31.1 |
1,198 |
34.7 |
|
|
35 – 39 |
79 |
26.2 |
734 |
21.3 |
|
|
≥ 40 |
69 |
22.9 |
734 |
21.3 |
|
|
Geographic origin |
|
|
|
|
|
|
France |
179 |
49.2 |
2,325 |
58.6 |
<0.001 |
|
North Africa |
66 |
18.1 |
416 |
10.5 |
|
|
Subsaharan Africa |
38 |
10.4 |
529 |
13.3 |
|
|
Other |
81 |
22.3 |
700 |
17.6 |
|
|
Occupation |
|
|
|
|
|
|
None |
24 |
7.6 |
281 |
7.4 |
0.014 |
|
Professional |
110 |
34.6 |
1,474 |
38.6 |
|
|
Intermediate |
44 |
13.8 |
566 |
14.8 |
|
|
Administrative/public service |
28 |
8.8 |
479 |
12.5 |
|
|
Other |
112 |
35.2 |
1,020 |
26.7 |
|
Pregnancy |
Outcome |
|
|
|
|
|
|
Still-births |
18 |
4.5 |
7 |
0.2 |
<0.001 |
|
Live-births |
269 |
66.6 |
4,231 |
99.6 |
|
|
Pregnancy terminations |
117 |
29.0 |
12 |
0.3 |
|
Art |
None |
369 |
93.4 |
3,959 |
96.5 |
0.004 |
|
IO$ only |
11 |
2.8 |
77 |
1.9 |
|
|
IVF£ only |
10 |
2.5 |
55 |
1.3 |
|
IVF+ICSI¥ | 5 | 1.3 | 13 | 0.3 |
*n represents the number of cases or controls without missing data.
§% calculated with the number of cases or controls without missing data as a denominator.
$Inductors of ovulation.
£In vitro fertilization.
¥IVF with intracytoplasmic sperm injection.