Figure 7. Induction of ARHI induces tumor dormancy in human ovarian cancer xenografts. (A) The control and dormancy groups were provided without DOX or with DOX in their drinking water. In the recurrence group, DOX was withdrawn after 32 d of treatment. Arrowheads indicate the day of DOX withdrawal. The results shown were from three independent experiments. *Compared with the control group, P < 0.01. ^##Compared with the recurrence group, P < 0.01. (B) LC3-I, LC3-II and ARHI expression in the three groups were detected by Western Blot. *Compared with the control group, P < 0.05. ^#Compared with the recurrence group, P < 0.05 (C) PCNA (a cell proliferation marker) and CD31 (an angiogenesis marker) expression detected by immunohistochemistry.